Barely Significant
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Evaluation of Expression and Clinicopathological Relevance of Small Nucleolar RNAs (snoRNAs) in Invasive Breast Cancer.

Noncoding RNA · 2025 · PMC12642022 · PMID 41283331

Europe PMCDOI
3
hedged sentences
0.1264
closest p · 2.5× alpha
0.1264
boldest claim

The sentences

showed a trendp = 0.1264not close (p > 0.1)
SNORA68 showed a trend to downregulation between stage I and IV ( p = 0.1264) and between stage II and IV ( p = 0.0790).

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did not reach statistical significanceno p-value reported
Expression levels of RNU2-1, SCARNA3, and SNORD15B were also higher in Ki-67-positive samples at both cut-offs, although these differences did not reach statistical significance.

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a decreasing trendno p-value reported
The significantly lower expression of RNU2-1 in lymph node metastasis-positive samples, along with a decreasing trend observed for SCARNA2, SNORD15B, and SNORD94, as well as the reduced expression of SNORD15B in multifocality-positive samples, all support the presumed tumor suppressor roles of these genes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.