Systematic Review and Meta-Analysis of the Management of Relapsed Germ Cell Tumours Following Cisplatin-Based Chemotherapy.

Oncol Ther · 2025 · PMC12647420 · PMID 41129007

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

In this systematic review, across all treatment settings combined, we found a trend toward improved survival outcomes with CDCT compared with HDCT, although these differences did not reach statistical significance across pooled data.

also in 111,027 other papers

showed a trendno p-value reported

reported a significant improvement in 5-year OS with the addition of radiotherapy to chemotherapy (72% versus 30%, p = 0.004), while the inclusion of surgery showed a trend toward improved survival (5-year OS 62.5% versus 38%), supporting the potential benefit of multimodality treatment in appropriately selected cases [ 78 ].

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.