A self-designed Chinese herbal formula alleviates GAstV infection-induced gout in goslings by inhibiting xanthine oxidase (XOD) and regulating intestinal microbiota.

Although a decline in viral loads was observed in fecal samples, the reduction did not reach statistical significance (P > 0.05).

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In this experiment, except for some unclassified and unnamed bacterial genera, Shigella, Acinetobacter, Escherichia, Corynebacterium freneyi and Globicatella sanguinis exhibited a statistical correlation trend of negative association with the levels of ALT, AST, CRE, BUN, and UA in the serum of goslings ( P < 0.05); correspondingly, these genera showed a trend of positive association with the protection rate.In contrast, Oceanobacillus and Sporolactobacillus showed a trend of positive association with the contents of ALT, AST, CRE, BUN, and UA in the serum, and a trend of negative association with the protection rate ( P < 0.05) ( Fig. 10 G).

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