Kidney replacement therapy and mortality in metformin-associated lactic acidosis with acute kidney injury (2015-2021): a multi-year cohort study.

Ren Fail · 2025 · PMC12649771 · PMID 41287211

Europe PMC DOI

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showed a trendno p-value reported

HD was the most effective treatment in MALA–AKI, early KRT initiation (<6 h) showed a trend toward lower mortality and oliguria, prolonged prothrombin time, and higher SOFA scores were identified as prognostic markers.

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did not reach statistical significanceno p-value reported

In our cohort, while we observed a trend toward lower mortality in patients receiving ‘early’ KRT (within 6 h of admission), this difference did not reach statistical significance.

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