rTg4510 Tauopathy Mice Exhibit Non-Spatial Memory Deficits Prevented by Doxycycline Treatment.

Repeated-measures ANOVA across all sessions and all four groups showed a trend toward group differences (F(3, 31) = 2.59, p = 0.071), without a significant group × session interaction (F(27, 279) = 0.89, p = 0.63).

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Distance traveled tended to be higher in rTg4510 mice without DOX, although this did not reach statistical significance ( Figure 1 A; F(3, 32) = 1.42, p = 0.26; all post-hoc p > 0.2).

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