Barely Significant
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Analysis of the Relationship Between <i>CHRNA</i>3/5 and <i>EPHX1</i> Polymorphisms to Tobacco Intake and Development of Chronic Obstructive Pulmonary Disease (COPD).

Biomedicines · 2025 · PMC12650495 · PMID 41301874

Europe PMCDOI
2
hedged sentences
0.1100
closest p · 2.2× alpha
0.1100
boldest claim

The sentences

did not reach statistical significancep = 0.11not close (p > 0.1)
Although the frequency of the risk alleles A (rs1051730) and C (rs8034191) was higher among individuals with heavy tobacco intake (>40 pack-years), the differences did not reach statistical significance ( p = 0.11 and p = 0.10, respectively).

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showed a trendno p-value reported
The CHRNA3 variants (rs1051730 and rs8034191) showed a trend toward higher prevalence among individuals with heavy tobacco intake (>40 pack-years), though no significant allelic or genotypic differences were found between COPD and control groups ( p > 0.05).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.