Preliminary Evaluation of the Gut Microbiota Modulatory Potential of Malaysian Kefir Water in Ageing Mice.

Foods · 2025 · PMC12651598 · PMID 41300008

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showed a trendno p-value reported

Both kefir water treatments, however, showed a trend toward reduced abundance of Lachnospiraceae NK4A136 group (Kefir+D-gal: 0.059 ± 0.023; pre-Kefir+D-gal: 0.030 ± 0.006) and Prevotellaceae UCG-001 (Kefir+D-gal: 0.037 ± 0.006; pre-Kefir+D-gal: 0.063 ± 0.031) compared to the D-gal-treated group ( Lachnospiraceae NK4A136: 0.113 ± 0.014, p = 0.125; Prevotellaceae UCG-001: 0.089 ± 0.010, p = 0.271).

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did not reach statistical significanceno p-value reported

While these findings did not reach statistical significance, likely due to the limited sample size and short duration of D-gal exposure, they indicate that kefir water may exert mild modulatory effects on gut microbial composition, potentially counteracting early signs of D-gal-induced dysbiosis.

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