Integrating Renal and Metabolic Parameters into a Derived Risk Score for Hyperuricemia in Uncontrolled Type 2 Diabetes: A Retrospective Cross-Sectional Study in Northwest Romania.

Medicina (Kaunas) · 2025 · PMC12654377 · PMID 41303877

Europe PMC DOI

hedged sentences

0.0690

closest p · 1.4× alpha

0.4630

boldest claim

The sentences

a near-significant trendp = 0.069so close (0.05 < p ≤ 0.1)

No significant differences were observed in urban–rural distribution, lipid-lowering therapy, or uric acid–lowering therapy, although the latter showed a near-significant trend ( p = 0.069). 3.1.

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did not reach statistical significancep = 0.463not close (p > 0.1)

Serum urea was identified as an independent an integrative indicator of renal–metabolic stress in uncontrolled T2D (OR = 1.045, 95% CI: 1.005–1.084, p = 0.027), while the triglyceride-to-LDL cholesterol ratio did not reach statistical significance in the adjusted model ( p = 0.463).

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