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Neutralizing Antibody Response Characteristics in Elderly Patients with SARS-CoV-2 Infection and Their Association with Clinical Phenotypes.

Vaccines (Basel) · 2025 · PMC12656855 · PMID 41295480

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showed a trendno p-value reported
In a multivariate logistic regression model adjusted for age, sex, comorbidities, and disease duration, vaccination showed a trend toward a 19.4% reduction in the risk of severe disease (OR = 0.806).

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The three-dose group showed a stronger NAb response than the two-dose group, although the difference did not reach statistical significance ( Figure 2 B), possibly due to heterogeneity in immune responses among the elderly.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.