Integrated analysis of N-glycosylation and Alzheimer's disease: identifying key biomarkers and mechanisms.

Front Aging Neurosci · 2025 · PMC12657396 · PMID 41323652

Europe PMC DOI

hedged sentences

0.0002

closest p · 0.0× alpha

0.0775

boldest claim

The sentences

highly significantp = 0.00019actually significant

The interaction between MLEC and TMEM59 was highly significant ( p = 0.00019, β = 2.469), with higher expression of both genes correlating with increased predicted probabilities ( Figure 10I ).

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near-significantP = 0.0775so close (0.05 < p ≤ 0.1)

The interaction between MGAT3 and MGAT1 ( Figure 11H ) also showed a near-significant effect ( P = 0.0775, β = 2.767).

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did not reach statistical significanceno p-value reported

While some interactions, such as MAX × MLEC ( p = 0.3604, β = –1.439) and APP × MGAT3 ( p = 0.3216, β = –0.827), did not reach statistical significance, they suggested potential regulatory trends worth further investigation ( Figures 10J,K ).

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