Gene polymorphisms associated with corneal curvature, astigmatism and its vector components in children.

There was also a significant trend of the protective effect of NHSL1 rs4896367 on IA, but at a nominal level ( P = 0.0110, Supplementary Table 3 ).

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A P value of <0.05 was considered nominally significant, and to account for multiple comparisons, we applied the Bonferroni correction, establishing a threshold of <0.00357 (0.05/14) to indicate study-wide significance for each separate analysis.

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