Barely Significant
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Survival impact of anti-CD38-based quadruplet regimens in transplant-ineligible newly diagnosed multiple myeloma: a network meta-analysis and reconstructed individual patient data meta-analysis.

Blood Cancer J · 2025 · PMC12681503 · PMID 41353340

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did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)
showed a trendno p-value reported
When compared with D-Rd, both regimens showed a trend toward improved OS; however, these differences did not reach statistical significance (HR 0.69; 95% CI, 0.47–1.03; P = 0.06, and HR 0.76; 95% CI, 0.57–1.02; P = 0.06, respectively).

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