Barely Significant
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Molecular biomarkers of sintilimab plus lenvatinib in hepatitis-B-virus-associated hepatocellular carcinoma.

World J Hepatol · 2025 · PMC12683347 · PMID 41368112

Europe PMCDOI
3
hedged sentences
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

approached significanceP < 0.10so close (0.05 < p ≤ 0.1)
DEG-immune cell analysis showed positive correlations with pro-B and plasma cells in responders, and negative correlations with CD4+ central memory T (Tcm), T helper 1, and natural killer T cells in non-responders; none significantly predicted PFS, although CD4+ Tcm cells approached significance ( P < 0.10).

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failed to reach significanceno p-value reported
Similarly, expression differences in natural killer T, T helper 1, and CD4+ Tcm cells also failed to reach significance in relation to PFS (Figure 3C - E ).

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did not reach statistical significanceno p-value reported
Unfortunately, the differences in the high or low scores of pro-B cells, class-switched memory B cells, and plasma cells did not reach statistical significance with respect to PFS (Figure 2B - D ).

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