A Prospective Cohort Study of Hepatitis B Virus Vaccination in Pediatric Heart Transplant Recipients: Cellular and Humoral Immune Responses and the Role of Innate Immunity.

Pediatr Infect Dis J · 2026 · PMC12688465 · PMID 40928222

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showed a trendno p-value reported

The analysis of corticosteroid impact showed a trend toward reduced immune response in patients receiving corticosteroids.

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did not reach statistical significanceno p-value reported

The subgroup of patients who received 3 or 4 vaccine doses showed a higher prevalence of seroprotection (3/10, 61.5%) and higher anti-HBs titers [median, 16.4 (IQR, 0–294.8) mIU/mL] compared with those who received 1 or 2 doses [8/13, 30% seroprotection; median, 0 (IQR, 0–23.7) mIU/mL] after post-SOT vaccination although these differences did not reach statistical significance (Fig. 1 A).

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