The Drosophila SIFamide Receptor Regulates Sleep and Feeding in a Time-Of-Day Specific Manner.

Consistent with our results from the FLIC assay, SIFaR mutants showed a trend towards elevated food intake (Brown‐Forsythe ANOVA revealed a significant main effect of genotype on food consumption ( F 4,49.59 = 3.907, p = 0.0078), although individual pairwise comparisons did not maintain significance after multiple test correction; Figure 5D ).

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Subjective day activity also trended slightly higher in SIFaR mutants, but this did not reach statistical significance compared to all control groups (Figure 3B ).

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