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Exercise-Dependent effects of substance P deficiency on joint degeneration and inflammation in a surgical mouse model of osteoarthritis.

Arthritis Res Ther · 2025 · PMC12699830 · PMID 41345957

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showed a trendno p-value reported
showed a trend toward reduction in KO Sham mice following intense exercise and in WT mice after DMM with moderate exercise (Fig. 7 E).

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Subchondral bone plate (SBP) thickness exhibited similar trends of increase pattern following DMM, although differences did not reach statistical significance (Fig. 6 D).

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