Tumor-Derived CXCL10 and CCL20 Polarize the Immune Microenvironment in Nasopharyngeal Carcinoma via Competitive Recruitment of Effector T Cells and Tregs.

CXCL10 high expression showed a trend toward prognostic relevance in HNSCC and was indicative of a survival difference in NPC (Figure 1 K-L).

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High expression of CCL20 in HNSCC was associated with poorer overall survival (OS) (Figure 1 I), and in NPC, it was associated with a trend toward reduced progression-free survival (PFS), though the result did not reach statistical significance (Figure 1 J).

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