Barely Significant
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Insulin Resistance and Blood Pressure Control on Cognitive Outcomes.

Hypertension · 2026 · PMC12711269 · PMID 41293821

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Additionally, for the annualized total brain volume change, the interaction term approached but did not reach statistical significance ( P for interaction=0.076).

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approached significanceno p-value reported
For the composite outcome of PD or MCI, the interaction approached significance ( P for interaction=0.088), suggesting a potential differential effect that warrants cautious interpretation.

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an increasing trendno p-value reported
Global cerebral blood flow demonstrated an increasing trend with intensive SBP intervention across baseline TyG index tertiles ( P for interaction=0.579; Figure 3 ).

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