Transcytotic transportation of size-controlled nanocarriers into dystrophic skeletal muscle leads to therapeutic outcome in mice.

We observed a trend toward reduced particle biodistribution in the quadriceps (~20% reduction) following macrophage depletion, although this difference did not reach statistical significance.

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While TMX NPs showed a trend of improvement over the free drug (Supplementary Fig. 13B ), the p -value did not reach statistical significance.

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