Quantitative Sensory Testing Reveals Evidence of Altered Pain Processing in Paget's Disease of Bone.

Warm and cool temperature stimuli showed a trend toward increased sensitivity over affected sites, but these differences did not reach the adjusted threshold for statistical significance (warm roller VAS: p = 0.049; cool roller VAS: p = 0.091).

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Pain VAS scores also differed between affected and unaffected sites ( p = 0.036), although other differences did not reach statistical significance in this smaller sample (Table 4 ).

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