Prognostic significance of the neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI) and panimmune-inflammation value (PIV) in head and neck squamous cell carcinoma (HNSCC): A retrospective cohort study.

Sci Prog · 2025 · PMC12715109 · PMID 41410881

Europe PMC DOI

hedged sentences

0.0517

closest p · 1.0× alpha

0.0760

boldest claim

The sentences

did not reach statistical significancep = 0.0517so close (0.05 < p ≤ 0.1)

1.04 ± 0.72), the result approached but did not reach statistical significance (p = 0.0517).

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approached significancep = 0.076so close (0.05 < p ≤ 0.1)

The SIRI (≥1.6) approached significance for OS (HR = 2.51, 95% CI: 0.91–6.93, p = 0.076) and was significant for DSS (HR = 3.33, 95% CI: 1.12–9.92, p = 0.031).

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