Soquelitinib inhibition of IL-2-inducible T cell kinase ameliorates lung damage in murine models of systemic sclerosis.

While both doses of SQL reduced collagen deposit, the effect did not reach statistical significance (Fig. 1 E).

also in 111,027 other papers

While SQL showed a trend toward improved lung function on imaging and modest effects on collagen deposits, it significantly reduced PAH in the Fra-2 mice, improving key cardiac hemodynamic parameters and showing trends of beneficial effects on vascular remodeling.

also in 53,322 other papers