An Exploratory Study of Cannabidiol as an Adjunctive Treatment for Refractory Epilepsy in Dogs.

The Friedman test revealed a highly significant reduction in clusters in the whole cohort (p < 0.0001), as well as in both the SE ( p = 0.0163) and IE ( p = 0.0102) subgroups ( Table 1 , Figure 4 ).

also in 132,142 other papers

However, a direct pre-post comparison using the Wilcoxon signed-rank test showed only a strong trend in the IE subgroup ( p = 0.057) and a non-significant change in the SE subgroup ( p = 0.174), suggesting that the Friedman test captured a substantial temporal effect driven by a sustained decrease. 3.3.

also in 5,725 other papers

Although the observed abnormal baseline and elevated ALT levels in certain dogs, particularly during the initial four weeks, did not reach statistical significance, they may suggest hepatotoxic interactions between CBD and conventional AEDs.

also in 111,027 other papers