Evaluation of Long-Term Outcomes of Enamel Matrix Derivative in the Treatment of Peri-Implant Disease: A Systematic Review and Meta-Analysis.

Bioengineering (Basel) · 2025 · PMC12729878 · PMID 41463593

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showed a trendno p-value reported

Although EMD consistently showed a trend toward improved clinical and radiographic outcomes, most differences did not reach statistical significance.

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a positive trendno p-value reported

did not reach statistical significanceno p-value reported

This suggests a positive trend toward improved outcomes with EMD, though the effect did not reach statistical significance at the pooled level.

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