Barely Significant
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Long-Term Enzyme Replacement Therapy and Renal Outcomes in Fabry Disease: A Systematic Review and Meta-Analysis.

Biomedicines · 2025 · PMC12730587 · PMID 41463002

2
hedged sentences
0.1700
closest p · 3.4× alpha
0.1700
boldest claim

The sentences

did not reach statistical significancep = 0.170not close (p > 0.1)
This pooled analysis yielded a weighted mean effect size of 0.037, which did not reach statistical significance ( p = 0.170) ( Figure 6 ).

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showed a trendno p-value reported
Although not statistically significant, our analysis showed a trend toward a faster eGFR decline rate in the untreated patient group compared to the treated group.

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