Deconstructing Therapeutic Failure with Inhaled Therapy in Hospitalized Patients: Phenotypes, Risk Profiles, and Clinical Inertia.

Biomedicines · 2025 · PMC12731047 · PMID 41462906

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.0770

boldest claim

The sentences

a strong trendp = 0.077so close (0.05 < p ≤ 0.1)

Regarding the effect of the type of device, in Cluster 2 “Assessed/Younger” phenotype, pre-admission use of a Spacer was associated with a strong trend towards an increased risk of errors ( p = 0.077), and pre-admission use of a DPI was associated with a modest, non-significant reduction in errors ( p = 0.11).

also in 5,725 other papers

did not reach statistical significancep = 0.077so close (0.05 < p ≤ 0.1)

The pre-admission use of a Spacer was associated with a trend toward an increased risk of errors, although it did not reach statistical significance ( p = 0.077).

also in 111,027 other papers

highly significantno p-value reported

This transition is clinically highly significant, as it represents a deliberate and evidence-based decision likely made during the in-hospital assessment.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.