CCL18: a potential immunosuppressive biomarker for prognosis in ABC diffuse large B-cell lymphoma.

Consistent with our previous findings ( Figure 3A ), additional validation analyses showed a trend toward eosinophil enrichment ( p = 0.23) and CD4 memory activated ( p < 0.01) in the ABC subtype, and a significant enrichment of M0 macrophages in the GCB subtype ( Supplementary Figure 5A ).

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Consistently, high MAPK10 levels were also associated with shorter progression-free survival (PFS) in the overall cohort ( p = 0.028; Figure 5C ), although this trend did not reach statistical significance when restricted to ABC cases ( p = 0.29; Figure 5D ) or GCB cases ( Supplementary Figure 4D ).

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