Perinatal outcomes in pregnancies with very and extremely advanced maternal age: An Italian multicenter retrospective cohort study.

Acta Obstet Gynecol Scand · 2026 · PMC12746181 · PMID 41225755

Europe PMC DOI

hedged sentences

0.1500

closest p · 3.0× alpha

0.1500

boldest claim

The sentences

did not reach statistical significancep = 0.150not close (p > 0.1)

While CS rates were higher in ART‐HE pregnancies in the unadjusted model (OR 1.54, 95% CI: 0.96–2.48), this association did not reach statistical significance after adjustment (aOR 1.43, 95% CI: 0.87–2.34; p = 0.150) (Table 4 ). 4.

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a clear trendno p-value reported

1 European data reveal a shift in the average age at first childbirth, rising from 28.8 years in 2001 to 31.1 years in 2021, indicating a clear trend toward delayed motherhood. 2 In Italy, the average maternal age at first childbirth is 32.4 years. 3 Several factors contribute to this trend, including societal and professional shifts, as well as advancements in artificial reproductive technologies (ART). 4 , 5 , 6 , 7 Suc

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.