Unraveling Cytomegalovirus Drug Resistance in Transplant Patients by Targeting Deep Sequencing.

J Med Virol · 2026 · PMC12746535 · PMID 41459759

Europe PMC DOI

hedged sentences

0.0504

closest p · 1.0× alpha

0.1630

boldest claim

The sentences

borderline significantp = 0.0504so close (0.05 < p ≤ 0.1)

60%), with a borderline significant association (OR = 8.67, p = 0.0504), supporting the hypothesis that prolonged viral replication increases the risk of resistance development [ 22 ].

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showed a trendp = 0.0504so close (0.05 < p ≤ 0.1)

ARM presence was not significantly associated with viral load or mortality, though recurrent CMV reactivation showed a trend toward association ( p = 0.0504).

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a nonsignificant trendp = 0.163not close (p > 0.1)

VGCV showed a nonsignificant trend toward less frequent use in ARM‐positive patients (36% vs. 65%; p = 0.163).

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did not reach statistical significanceno p-value reported

A similar trend was observed for VGCV (OR = 0.30, p = 0.163), though it did not reach statistical significance [ 22 ].

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