Barely Significant
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Treatment outcomes and prognostic factors in external auditory canal squamous cell carcinoma.

PLoS One · 2025 · PMC12747381 · PMID 41460837

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Although these histological features did not reach statistical significance in our cohort, nodal metastasis demonstrated a borderline association with poorer outcomes, suggesting a potential role for the selective use of adjuvant therapy in high-risk patients.

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borderline significanceno p-value reported
Carotid artery abutment (HR = 16.41, p = 0.050), jugular bulb abutment (HR = 9.01, p = 0.067), and N stage (HR = 4.40, p = 0.096) showed borderline significance, indicating a trend toward increased risk of mortality.

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approached significanceno p-value reported
Significant predictors of decreased survival included younger age and carotid artery abutment, while jugular bulb abutment and N stage approached significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.