Interestingly, even hypoxia‐like state markers that did not reach statistical significance—such as HCT—showed directional improvements with moderate effect sizes, reinforcing a coherent physiological narrative.
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Impact of dietary intervention and supplementation on the physiological profile of individuals with down syndrome.
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The sentences
Thus, post-intervention values demonstrate a clear trend toward established biochemical reference ranges, indicating partial metabolic normalization and may underlie broader, multi-systemic improvements, suggesting a promising therapeutic avenue for neurodevelopmental disorders 79 .