Preoperative Cannabis Use and Ankle ORIF Outcomes: Higher Risks of Infection, Nonunion, and Reoperation.

Foot Ankle Int · 2026 · PMC12754024 · PMID 41243321

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approached significantno p-value reported

10 , 15 , 20 , 26 Hardware infection rates were significantly higher at 6 months and approached significant at 90 days and 3 years.

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approached significanceno p-value reported

Sepsis (0.90% vs 0.30%, P = .003) and hardware infection (1.90% vs 1.00%, P = .005) approached significance but did not meet the Bonferroni-adjusted threshold.

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approaching significanceno p-value reported

These measures were reported for outcomes meeting or approaching significance to provide clinically meaningful context alongside relative effect sizes.

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