Although the feminization trend observed after LPS immersion did not reach statistical significance, the molecular data support the hypothesis that immune activation during sex differentiation can influence the epigenetic landscape of key regulatory genes.
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Sexual dimorphism in the DNA methylation pattern after immune stimulation in the zebrafish (<i>Danio rerio</i>) gonads.
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The sentences
Results Immune stimulation during gonadal development did not produce a statistically significant difference in sex ratio, although a clear trend toward feminization was observed in LPS-treated fish.