Prognostic impact of restrictive ventilatory defects in chronic lung allograft dysfunction without restrictive allograft syndrome-like opacities: Stratification of emerging undefined and unclassified phenotypes.

In multivariable Cox analysis of non-RLO patients, restrictive ventilatory defects showed a trend toward worse outcomes (Hazard ratio [HR]: 2.56, 95% CI: 0.98–6.71; p = 0.055), while obstructive defects showed no association (HR: 0.88, p = 0.785).

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Association between radiographic findings and restrictive ventilatory defects In univariate analysis, the associations between restrictive ventilatory defects ( Figure 2B : b1, b2) and both diaphragmatic elevation ( p = 0.163) and pleural effusion ( p = 0.063) did not reach statistical significance.

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