Protective association of renin-angiotensin system inhibitor use with skeletal muscle wasting in diabetic heart failure.

J Diabetes Investig · 2026 · PMC12757670 · PMID 41217949

Europe PMC DOI

hedged sentences

0.0920

closest p · 1.8× alpha

0.0920

boldest claim

The sentences

a trend towards significanceP = 0.092so close (0.05 < p ≤ 0.1)

The overall association of RCS‐modeled log‐3‐Me‐His with muscle wasting showed a trend towards significance when adjusted with CKD ( P = 0.092) and when adjusted with eGFR ( P = 0.067).

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did not reach statistical significanceP = 0.123not close (p > 0.1)

showed a trendno p-value reported

RASI use showed a trend towards lower odds of muscle wasting, although this association did not reach statistical significance (OR 0.70; 95% CI 0.44–1.10, P = 0.123).

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