Serum miR-493-3p as a diagnostic biomarker and epigenetic regulator targeting DPY30 in pediatric acute lymphoblastic leukemia.

Ann Hematol · 2025 · PMC12764696 · PMID 41249660

Europe PMC DOI

hedged sentences

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

showed a trendP = 0.078so close (0.05 < p ≤ 0.1)

Regarding BCR-ABL status, our data showed a trend toward higher positivity in the low miR-493-3p expression group (13/55, 23.6% vs. 5/48, 10.4%; P = 0.078), approaching but not reaching statistical significance.

also in 42,889 other papers

near-significantno p-value reported

The near-significant difference raises the possibility that expanding the sample size could enhance statistical power to confirm this association—however, this remains speculative and requires validation in larger, multi-center cohorts.

also in 2,024 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.