Although similar restorative trends were observed for P-ERK, GluN1, P-JNK, P-P38, and IL-1β, the differences between taVNS and fluoxetine did not reach statistical significance.
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Multi-omics reveals associations between the microbiota-gut-brain axis and antidepressant effects of vagus nerve stimulation.
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The gut microbiota of taVNS-treated rats showed a clear trend of regression ( Fig. 4 C).