The sphingolipid metabolite sphingosine protects against hypertension by targeting metabolic-inflammatory crosstalk via the NLRP3 inflammasome.

3 F), its overall predictive power did not reach statistical significance (P > 0.05) ( Fig. 3 H).

also in 111,027 other papers

An initial, unsupervised look at the data using Principal Component Analysis (PCA) was revealing: it showed a clear trend of separation between the HTN and CTR groups, suggesting a distinct metabolic fingerprint for hypertension ( Fig. 3 A and B).To sharpen this initial observation and pinpoint the molecules driving this difference, we built supervised OPLS-DA models.

also in 19,460 other papers