Downregulation of HLA Class I Expression through HLA-A DNA Methylation Is Associated with Reduced CD8+ T-cell Infiltration in Cervical Cancer.

Cancer Immunol Res · 2026 · PMC12780734 · PMID 41144789

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did not reach statistical significanceP = 0.063so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Within SCC cases, PD-L1–positive tumors showed a trend toward increased CD8 + T-cell infiltration compared with PD-L1–negative tumors, although this difference did not reach statistical significance ( P = 0.063; Fig. 3G ).

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