The Association Between Pre-cycle Maternal Vitamin D Status and Reproductive Outcomes in Frozen-Thawed Embryo Transfer: A Systematic Review and Meta-Analysis.

Cureus · 2026 · PMC12781137 · PMID 41523712

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

borderline non-significantp=0.08so close (0.05 < p ≤ 0.1)

The analysis may be underpowered to confirm smaller but clinically meaningful differences, particularly for the LBR, where a borderline non-significant trend (p=0.08) was observed.

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did not reach statistical significanceno p-value reported

In the overall pooled analysis, low vitamin D levels were associated with lower odds of clinical pregnancy; however, this association did not reach statistical significance (OR: 0.37, 95% CI: 0.12-1.08), likely due to substantial heterogeneity among studies (I2=92.7%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.