Plasma Short-Chain Fatty Acids and Cytokine Profiles in Chronic Kidney Disease: A Potential Pathophysiological Link.

Int J Mol Sci · 2026 · PMC12786690 · PMID 41516422

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0790

boldest claim

The sentences

a trend toward significancep = 0.068so close (0.05 < p ≤ 0.1)

A similar direction was observed for left ventricular ejection fraction, which showed a trend toward significance (OR = 0.97, p = 0.068).

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showed a trendp = 0.079so close (0.05 < p ≤ 0.1)

Among short-chain fatty acids, hexanoic acid (C6) showed a trend toward higher levels in sarcopenic patients ( p = 0.079).

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did not reach statistical significanceno p-value reported

Certain inflammatory cytokines (IL-4, IL-18) demonstrated numerical differences but did not reach statistical significance.

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