GluN2B-specific NMDAR positive allosteric modulation reverses cognitive and behavioral abnormalities in <i>Mecp2</i> and <i>Disc1</i> transgenic mice.

Following the 175 treatment, the social preference index in Mecp2-OE mice was mildly improved (0.12 ± 0.12 versus −0.08 ± 0.25) but did not reach statistical significance ( Fig. 5I ).

also in 111,027 other papers

Mecp2-OE mice treated with Veh exhibited a strong trend toward impaired social cognition compared with WT mice, based on the preference index ( Fig. 5, K and L ).

also in 5,725 other papers