Blood-brain barrier integrity and prevalence of intrathecal T helper 17.1 cells in Huntington´s disease.

PLoS One · 2026 · PMC12795374 · PMID 41525278

Europe PMC DOI

hedged sentences

0.7700

closest p · 15.4× alpha

0.7700

boldest claim

The sentences

did not reach statistical significancep = 0.77not close (p > 0.1)

However, these group differences did not reach statistical significance (p = 0.77; Fig 3 ).

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showed a trendno p-value reported

Moreover, the same study using dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) showed a trend towards increased BBB permeability in the caudate nucleus and putamen, and a significant positive correlation between increased BBB permeability in the caudate nucleus and disease burden score in HDGECs [ 23 ].

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