OPG-Producing B Cells and RANKL-Expressing T Cells Define Immune Signatures Predictive of Bone Metastases in Breast Cancer.

Cancer Res Commun · 2026 · PMC12795788 · PMID 41364090

Europe PMC DOI

hedged sentences

0.1323

closest p · 2.6× alpha

0.1323

boldest claim

The sentences

did not reach statistical significanceP = 0.1323not close (p > 0.1)

9E ) did not reach statistical significance ( P = 0.1323, unpaired t test).

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a clear trendno p-value reported

However, a clear trend was observed for increased infiltration of CD20 + B cells in tumors from patients who did not develop bone metastases (median: 35.66% vs. 23.97%; Fig. 9E ).

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