Ratios of CD8 T lymphocytes to M-MDSCs (CD8MMR) predict prognosis in patients with untreated DLBCL.

Blood Neoplasia · 2026 · PMC12796983 · PMID 41536781

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did not reach statistical significanceno p-value reported

Among patients with DLBCL with the GCB subtype ( Figure 4 E-F), low CD8MMR was also associated with significantly inferior PFS, although the difference in OS did not reach statistical significance.

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showed a trendno p-value reported

Otherwise, male patients tended to have lower LMR levels than female patients; patients with the non-GCB subtype showed a trend toward lower levels of CD4MMR and CD8MMR than those with the GCB subtype; patients with BM involvement exhibited a trend of lower LMR, CD4MMR, and CD8MMR than those without such involvement.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.