(2024) due to the same reasons as previously stated, the pooled analysis of two observational studies also showed a trend towards reduced risk of bleeding in the reduced dose of enoxaparin, as compared with the standard dose of enoxaparin (Supplementary Fig. 6 ), but did not reach statistical significance [RR 0.34, 95% CI 0.06–1.84, I 2 = 38%].
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Efficacy and safety of anticoagulation dose reduction for venous thromboembolism prophylaxis in low body weight patients: a systematic review and meta-analysis.
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4 ), but this did not reach statistical significance [RR 0.6, 95% CI 0.34–1.06], with low heterogeneity (I 2 = 0%).