APOBEC3B protein expression associates with poor prognosis for breast cancer patients with ER-positive disease.

Breast Cancer Res · 2025 · PMC12802011 · PMID 41366803

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a significant trendno p-value reported

Also, we found a significant trend between A3B protein expression and tumor size, tumor grade and mitotic rate.

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borderline significantno p-value reported

In addition, there was a borderline significant shorter DFS (HR = 1.36; 95%CI = 0.96–1.95) found in A3B-high samples compared to A3B-low samples.

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a clear trendno p-value reported

In the supplementary analyses, we also studied the group who had a A3B positive expression of more than 25%, showing a clear trend of increasing A3B expression and worse outcome.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.