Plasma glial fibrillary acidic protein (GFAP) is a biomarker for central nervous system involvement in infantile-onset Pompe disease.

EBioMedicine · 2026 · PMC12805081 · PMID 41483684

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did not reach statistical significancep = 0.55not close (p > 0.1)

showed a trendno p-value reported

Although plasma GFAP levels showed a trend toward improved classification of disease severity, the difference compared with plasma NfL levels did not reach statistical significance (p = 0.55).

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