Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2-Dependent Modulation of Subthreshold Currents.

J Neurochem · 2026 · PMC12817328 · PMID 41556370

Europe PMC DOI

hedged sentences

0.0746

closest p · 1.5× alpha

0.0746

boldest claim

The sentences

did not reach statistical significancep = 0.0746so close (0.05 < p ≤ 0.1)

This mitigating effect is evident in the data, even though it did not reach statistical significance in the non‐parametric Mann–Whitney U test (K_Pst, p = 0.0746; Figure 7B and Table S3 ).

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showed a trendno p-value reported

In both subtypes, sevoflurane showed a trend in decreasing steady‐state current amplitudes, with a stronger suppression from −67 to −47 mV (Figure 6C–E ).

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