116 However, while the association between post-traumatic stress disorder and exosomal tau levels showed a trend, it did not reach statistical significance. 116 Further research into exosomal p-tau-181 in 195 veterans with repeated mTBI found a weak, significant correlation with the total PCL-M score (PTSD checklist military version).
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Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers.
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While no significant associations were found between GFAP or NfL levels and cognitive outcomes overall, in the SRC group, moderate GFAP levels at 26 weeks showed a borderline significant link to slower identification task (latency), while extreme and minimally elevated NfL levels at 26 weeks were significantly associated with slower identification task (latency), but moderate NfL levels were not. 104 The lack of consistent associations with moderate NfL levels suggests that this relationship may vary.